Scientists Shed Light on Potential Treatment for Gaucher’s Disease

Ancient Gut Microbiomes Shed Light on Modern Disease

A 118 microbial agents ancient gut microbiomes shed light on modern Disease People in westernized, urban environments host different gut microbes than people in remote, undeveloped parts of the world. Children in remote regions of Burkina Faso, for instance, have been shown to harbor bacteria alien to the guts of Europeans. A similar pattern has been found in comparing the microbiomes of rural ...

Quantum dots shed light on diagnoses.

Featured article: Kim S, Lim YT, Soltesz EG, De Grand AM, Lee J, Nakayama A, Parker JA, Mihaljevic T, Laurence RG, Dor DM, Cohn LH, Bawendi MG, Frangioni JV. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol 2004;22:93–7. Near-infrared (NIR) (700 –2500 nm) in vivo imaging with semiconductor quantum dots (QDs) can offer nonradioactive extraction of me...

Genotype networks shed light on evolutionary constraints.

An evolutionary constraint is a bias or limitation in phenotypic variation that a biological system produces. One can distinguish physicochemical, selective, genetic and developmental causes of such constraints. Here, I discuss these causes in three classes of system that bring forth many phenotypic traits and evolutionary innovations: regulatory circuits, macromolecules and metabolic networks....

Gauchers disease presenting with portal hypertension.

Gauchers disease is a rare lysosomal storage disorder characterized by abnormal accumulation of lipid-laden macrophages in different organs. Though hepatosplenomegaly is commonly found, symptomatic presentation with portal hypertension is rare. We report a child with liver cirrhosis and bleeding esophageal varices who was diagnosed with Gaucher's disease.

Studies shed light on sunscreen efficacy.